The International Microbiome Centre (IMC) Imaging platform provides imaging with highly specialized expertise in visualization of microbes and immune cells using real time intravital imaging.
Our vision is to use intravital imaging to harness the power of the microbiome for better living.
Our mission is to use intravital imaging for microbiome research to gain a detailed understanding of the effect of the microbiome on immune cell location and function in healthy and chronic disease models. In alignment with the overall IMC mission, the imaging platform also offers the latest cutting-edge technologies for advancement of microbiome research to a broad audience of researchers (internal and external), industry and government including animal health, agriculture, energy and the environment. IMC promotes standardization of intravital imaging protocols and is developing a global network for development of collaborations and partnerships to further enable translation of microbiome research.
Key Areas of Research
Microbiome & Chronic disease
Infammatory bowel disease
Type 1 Diabetes
Cancer and cancer immuno-therapies
Antibody panel design (human and mouse)
Antibody labelling for mass cytometry
Acquisition of samples
Data analysis support by IMC bioinformatics platform
Dr. Paul Kubes, PhD, Director of Imaging, IMC
Paul Kubes is a Professor at the University of Calgary, Cumming School Medicine and the Founding Director of the Snyder Institute for Chronic Diseases. He also holds a Canada Research Chair in Leukocyte Recruitment in infammatory disease. Dr. Kubes has received numerous awards including the CIHR Investigator of the Year in 2011 for his basic science work on how the brain affects immunity. He has also received the Alberta Science and Technology Award and the Henry Friesen Award. Dr. Kubes has published basic science work in Cell, Science and the Nature journals and also has publications in both clinical journals including Lancet and more translational journals (JCI). His latest work has uncovered a key role for peritoneal cavity macrophage in healing visceral organs.